Relevant Resources and Core Facilities
University Core Facilities
Genomics requires access to advance and ever-changing technology to generate and to analyze data. At Cornell, we have outstanding core facilities available to faculty, staff, students and postdocs doing or planning genomic analysis of all scales and organisms. An overview of genomics core laboratories is available here, with additional a broader summary provided below.
Cornell University Life Sciences Core Laboratories Center (CLC) provides an array of genomics, proteomics, imaging and informatics shared research resources and services to the Cornell University community and to outside investigators. The CLC includes fee-for-service research, technology testing and development, and educational components. The Center has seven biotechnology core facility laboratories, including genomics (DNA sequencing, genotyping, and microarrays), epigenomics, proteomics and mass spectrometry, microscopy and imaging, bio-IT (information technology), bioinformatics and computational biology, and advanced technology assessment.
DNA sequencing, genotyping, and microarray applications are provided by this facility under the direction of Dr. Peter Schweitzer. Sequencing instruments includes twp Illumina HiSeq 2000s, one Roche GS-FLX, and two ABI 3730xl capillary sequencers. SNP genotyping services are available using Illumina BeadArray and BeadXpress Readers, a Sequenom MassArray system, Affymetrix GeneChips, and ABI real-time PCR instrumentation. Nimblegen and Agilent array instrumentation is available for epigenomics and sequence-capture experiments. Data management and analysis can be coordinated with the Computational Biology Service Unit support group (CBSU).
Computational Biology Service Unit (CBSU)
The Computational Biology Service Unit at Cornell features several computer clusters as well as database and file servers for doing serious computational analyses, including custom BLAST and other searches, microarray analysis, and short-read sequence assembly and analysis. They provide excellent technical services and advice associated with these and related analysis problems.
Other Relevant Resources
Evolutionary Genetics Core Facility (EGCF) in Corson Hall
The EGCF is housed in room E347-351 Corson Hall. Designed primarily as a “training and testing” facility, the EGCF provides space, equipment, supplies and expertise to Cornell investigators interested in accessing the information found in DNA. Projects optimized and samples prepped in the EGCF can utilize services (“Ready-To-Load” sequencing and genotyping) and equipment (next generation sequencers, SNP detection systems) provided by the Genomics Core Laboratory in the Biotechnology Building for high-throughput data collection. The EGCF has expertise in Sanger sequencing, fluorescent genotyping, transcriptome (cDNA) preparation for Illumina HiSeq 2000 and Roche/454 sequencing, and the discovery of SNPs and microsatellites from non-model organisms. For more information, contact Steve Bogdanowicz (smb31 at cornell dot edu, 254-4297).
Cornell’s Natural History Collections
- Cornell University Museum of Vertebrates
- Bailey Hortorium
- Cornell University Insect Collection