Genomics Core Facilities at Cornell
Genomics requires access to advance and ever-changing technology to generate and to analyze data. At Cornell, we have outstanding core facilities available to faculty, staff, students and postdocs doing or planning genomic analysis of all scales and organisms. Outstanding, state-of-the-art Genomics shared core facilities are provided by Cornell's Biotechnology Resource Center (BRC) which maintains an array of genomic, proteomics, imaging and informatics shared research resources and Core Laboratory services to the university community.
About the BRC Genomics Facility: "The BRC Genomics Facility provides a broad array of instrumentation and services, including Sanger sequencing of plasmid and PCR products on the Life Technology/ABI 3730x1 capillary array sequencing platform, and a range of next generation sequencing instruments, such as the Illumina MiSeq and Illumina HiSeq 2000/2500 platforms. The facility also provides high throughput genotyping and gene expression services using the Illumina, Affymetrix and Agilent microarray platforms, plus real-time PCR system" (description taken from this BRC webpage.)
About the BRC Genomic Diversity Facility: "The BRC Genomic Diversity Facility provides expertise and state-of-the-art support for genotyping-by-sequencing (GBS) projects, including project optimization, library production, DNA sequencing and data analysis, to the university community and to outside investigators from academic institutions and non-commercial entities. The facility also provides consultation on project design and data analysis, and offers educational resources, workshops and training" (description taken from this BRC webpage).
Other Genomics Related Core Facilities at Cornell
The Evolutionary Genetics Core Facility: "The EGCF is primarily a “training and testing” facility. Investigators that have their project design optimized and/or samples prepped in the EGCF can then use the services of the BRC Genomics Facility for generating sequence and fragment analysis data and the resources of the BRC Bioinformatics Facility for computational and data analysis support. The EGCF has expertise in Sanger sequencing, fluorescent genotyping, transcriptome (cDNA) preparation for next generation sequencing, and the discovery of SNPs and microsatellites from non-model organisms. The EGCF is part of the Department of Ecology and Evolutionary Biology of Cornell University" ?(description taken from this BRC webpage.)
The RNA sequencing Core Facility: "The RSC offers custom support for RNA sequencing, including library preparation and data analysis. The RSC uses the services of the BRC Genomics Facility for generating RNA sequence data and the resources of the BRC Bioinformatics Facility for computational and data analysis support. The RSC is part of the Center for Reproductive Genomics and of the Department of Biomedical Sciences in the College of Veterinary Medicine of Cornell University" ?(description taken from this BRC webpage.)
Other Core Laboratories at Cornell
The Proteomics and Mass Spectrometry Facility: "The BRC Proteomics and Mass Spectrometry Facility provides investigators with cutting edge technologies for proteomic analyses. Services include 2D gel and 2D LC separation for macromolecules; robotic and manual sample preparation for proteomics samples; protein identification; quantitative proteomics by 2D DIGE analysis or shotgun-based iTRAQ; and characterization of post-translational modifications (PTMs) through both non-targeted and targeted discovery approaches. Services also include small molecule profiling, quantitation and data interpretation" (description taken from this BRC webpage).
The Imaging Facility: "The BRC Imaging Facility (formerly called variously Cornell Imaging, the CT Facility, the Imaging and Microscopy Facility, and the Microscopy Imaging and Fluorometry Facility or MIF) resources and services include high resolution X-ray computed tomography (CT), flow cytometry, confocal microscopy, light microscopy, multiphoton microscopy, laser capture microdissection, bioluminescence imaging, high resolution ultrasound imaging, spectrofluorometry, and image visualization and analysis software. The facility also provides consultation on project design, instrument use, and image data analysis and visualization, and offers educational workshops and training" (description taken from this BRC webpage).
The Bioinfomatics Facility: "The mission of the BRC Bioinformatics Facility (formerly called the Computational Biology Service Unit or the CBSU) is to support biological research with advanced computational infrastructure and bioinformatics tools and techniques. The facility was founded in 2001 as a computational biology resource for a Tri-Institutional collaboration among the Cornell University campus in Ithaca, NY, and the Weill Cornell Medical College, Rockefeller University, and the Memorial Sloan-Kettering Cancer Center in New York City, NY. The facility became part of the BRC in 2004. The Bioinformatics Facility offers resources, services and training in computational biology and bioinformatics through collaborative research and consultation, and by providing easily accessible advanced computational software, data storage and analysis platforms and expertise in their use and applications" (description taken from this BRC webpage).
The BRC Bio-IT Facility: "The BRC Bio-IT Facility supports the activities of the BRC core facilities with enterprise-level information technology (IT) infrastructure, laboratory information management systems, and data management and analysis services. The facility also provides desktop and network support, software license management, and custom bio-IT services to a diverse array of investigators in the Cornell University life sciences research community" (description taken from this BRC webpage).
The Advanced Technology Assessment Facility: "The mission of the BRC Advanced Technology Assessment Facility is to evaluate, implement and optimize newly emerging biotechnologies and protocols for their effective use, in close coordination with the other BRC core facilities. Once robust high throughput production pipelines are established, the new technologies are transferred to the appropriate BRC facility. This is essential for the successful implementation of newly available, high-end technologies that require extended evaluation, validation, development and optimization. The facility thus facilitates effective implementation of new technologies and novel applications with the potential for breakthrough discoveries in the life sciences" (description taken from this BRC webpage).